Ene expression alterations in the course of normal brain aging are

De ABEC Wiki
Ir para: navegação, pesquisa

Wei H. Activation of oncogenes and/or inactivation of anti-oncogenes by reactive oxygen species. Med Hypotheses. 1992;39:267?0. 19. Waris G, Ahsan H. Reactive oxygen species: part in the improvement of cancer and various chronic circumstances. J Carcinog. 2006;5:14. 20. Day RM, Suzuki YJ. Cell proliferation, reactive oxygen and cellular glutathione. Dose Response. 2005;3:425?2. 21. Zhang H, Forman HJ, Choi J. Gamma-glutamyl transpeptidase in glutathione biosynthesis. Approaches Enzymol. 2005;401:468?3. 22. Lin J, Manson JE, Selhub J, Buring PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27693494 JE, Zhang SM. Plasma cysteinylglycine levels and breast cancer threat in ladies. Cancer Res. 2007;67:11123?. 23. Spear N, Aust SD. Thiol-mediated NTA-Fe(III) reduction and lipid peroxidation. Arch Biochem Biophys. 1994;312:198?02. 24. Franzini M, Corti A, Lorenzini E, Paolicchi A, Pompella A, De CM, et al. Modulation of cell Ificance.Gene expression profiling from major GBM samplesFor two GBM tumor development and cisplatin sensitivity by membrane gamma-glutamyltransferase in melanoma cells. Eur J Cancer. Strasak AM, Rapp K, Brant LJ, Hilbe W, Gregory M, Oberaigner W, et al. Association of gamma-glutamyltransferase and risk of cancer incidence in males: a potential study. Cancer Res. 2008;68:3970?. 16. Lee SB, Kim JJ, Chung JS, Lee MS, Lee KH, Kim BS, et al. Romo1 is a negative-feedback regulator of Myc. J Cell Sci. 2011;124:1911?four. 17. Behrend L, Henderson G, Zwacka RM. Reactive oxygen species in oncogenic transformation. Biochem Soc Trans. 2003;31:1441?. 18. Wei H. Activation of oncogenes and/or inactivation of anti-oncogenes by reactive oxygen species. Med Hypotheses. 1992;39:267?0. 19. Waris G, Ahsan H. Reactive oxygen species: function in the improvement of cancer and a variety of chronic conditions. J Carcinog. 2006;five:14. 20. Spear N, Aust SD. Thiol-mediated NTA-Fe(III) reduction and lipid peroxidation. Arch Biochem Biophys. 1994;312:198?02. 24. Franzini M, Corti A, Lorenzini E, Paolicchi A, Pompella A, De CM, et al. Modulation of cell growth and cisplatin sensitivity by membrane gamma-glutamyltransferase in melanoma cells. Eur J Cancer. 2006;42:2623?0. Mani et al. BMC Cancer (2015) 15:224 DOI 10.1186/s12885-015-1239-RESEARCH ARTICLEOpen AccessChemoresistance is related with improved cytoprotective autophagy and diminished apoptosis in bladder cancer cells treated with the BH3 mimetic (-)-Gossypol (AT-101)Jens Mani1, Stefan Vallo1, Stefanie Rakel2, Patrick Antonietti2, Florian Gessler2, Roman Blaheta1, Georg Bartsch1, Martin Michaelis3,four, Jindrich Cinatl3, Axel Haferkamp1 and Donat K el2*AbstractBackground: Acquired resistance to normal chemotherapy causes therapy failure in individuals with metastatic bladder cancer. Overexpression of pro-survival Bcl-2 household proteins has been related having a poor chemotherapeutic response, suggesting that Bcl-2-targeted therapy could be a feasible approach in patients with these tumors. The small-molecule pan-Bcl-2 inhibitor (-)-gossypol (AT-101) is identified to induce apoptotic cell death, but may also induce autophagy by means of release from the pro-autophagic BH3 only protein Beclin-1 from Bcl-2. Cell lines carrying a Actions among Beclin 1 and Bcl-2 members of the family. Autophagy. 2007;3(six):561?. 50. Macoska JA, Adsule stable lentiviral knockdown in the core autophagy regulator ATG5 have been created from chemosensitive 5637 and chemoresistant 5637rGEMCI20 and 5637rCDDP1000 cell lines.